ACADEMIC YEAR: 2015-16 SEMESTER: V

CADEMIC YEAR: 2015-16 SEMESTER: V SCH 1 DIRECTOR OOL OF SCIENCE RK ... Lithium Aluminium Hydride LiAlH4 Sodamide ... Two solid components using water…...

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SCHOOL OF SCIENCE

SYLLABUS FOR

PROG OGRAM: B.Sc. CHEMISTRY

A ACADEMIC YEAR: 2015-16

SEMESTER: V

DIRECTOR SCH HOOL OF SCIENCE RK UNIVERSITY RAJKOT 1

Course Title

Chemistry

Course Code

BSC50 02

Course Credit

Lecture

:4

Practical

:3

Total

:7

Course Objectives On the completion of the course, students will be able to:  Understand reaction, rearrangement, reagent, natural product, drugs, dyes, symmetry & spectroscopy, heterocyclic chemistry. chemistry  Theoretical identification methods of organic molecules by UV & IR spectroscopy.  Separate out organic mixture by analytical method.  Choose proper method to separate mixture exist in two different state. Detailed Syllabus Sr. No. Name of Chapter & Details

Hours Allotted

SECTION-I Organic Chemistry 1

Name Reactions, Rearrangement and Reagents: 12 Reactions : Arndt Eistert Reaction, Bischler Napierski Reaction, Leuckart Wallach Reaction Rearrangements:: Hoffmann Rearrangement, Curtius Rearrangement, Rearrangement Fries Rearrangement Reagents: Lithium Aluminium Hydride LiAlH4 LiAlH4, Triphenyl phosphines, Sodamide

2

Alkaloids 12 Introduction, Occurrence, Classification, Isolation, General method of proving structure of Alkaloids, Constitution, Properties and Synthesis of ( Coniine,Nicotine, Papaverine)

2

3

Carbohydrates 11 Introduction, Classification and nomenclature, General reactions of Monosaccharides (with reference to Glucose and Fructose)Inter-conversions: Fructose)Inter (Conversion of Aldose to the corresponding Ketose, Conversion of Aldose to the next higher Ketose (Wolform method ), Conversion of Aldose to the Ketose having two more carbon atoms (Sowden method), Conversion of Ketose to the corresponding Aldose, Step-up Step up reactions (Ascending in Aldose series):, Kiliani Reaction, Swoden Nitromethane reaction, Step Step-down down reactions (Descending in Aldose series - Aldohexose to Aldopentose) by Ruff’s Method,Configuration of monosaccharides, Ring structure of Aldoses,Determination of ring size of Glucose by(a. Methylation method, b. Periodic oxidation method), Mutarotation of D (+) glucose

4

Synthetic Drugs, Dyes and Sweetening Agents Only Synthesis and Uses of Drugs:: Ibuprofen, Atenlol and Adrenaline Dyes:: Orange II, Crysodine G, Auramine O Sweetening Agents: Agents Saccharin, p-anisylurea and Dulcin

5

Synthesis of Heterocyclic Compounds containing two hetero atomsPreparation Preparation of: Pyrazole,Imidazole, Isoxazole, ,Thiazole, Pyrimidine, Pyridazine, Oxazine, Thiazine, Dioxane

SECTION-II Spectroscopy 1

Molecular symmetry Introduction, symmetry elements and symmetry operation with illustration, Definition of Properties of group , subgroup and classes, Products of symmetry 10 operations, Symmetry point group. (C1, Cs, Ci, Cn, Cnv, Cnh, Dn, Dnh, Dnd, C, Dh, h, Td, Oh), Multiplication tables for C2V, C3V and C2h point groups.

2

U.V. spectroscopy Introduction, Theory of ultra violate spectra, Instrumentation, Type of transition in organic molecules; auxochrome, chromophore; Explanation of bathochromic shift and hypsochromic shift, Hyper chromic effects, Types of 10 bands, Effect of solvent, franck condon principles, Application of UV spec spectra, Calculation of -max max (1) Dienes and conjugated dienes (2) enones and dienones ie. unsaturated carbonyl compounds, (3) aromatic carbonyl system

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3

Infra red Spectroscopy Introduction, Range of IR , theory of IR, Modes of fundamental vibration, IR active, force constant, Vibration coupling, Fermi resonance, Finger print region, Instrumentation, Application of IR, Structure of organic molecules 10 From IR, Interpretation of IR for given molecules and problems

Laboratory course CHEMISTRY PRACTICALS SYLLABUS Organic Separation ( Mixture of two compounds ) [35 marks] [Minimum 12 mixtures should be done] Separation & Analysis of an organic mixture containing: (a) Two solid components using water, NaHCO3, NaOH and HCl for separation (b) Liquid + liquid component - separation by physical method. (c) Liquid + solid component - separation by physical method. Instructional Method and Pedagogy:     

Lectures will be conducted with the aid of multi-media multi media projector, black board, OHP etc. Assignments based on course content will be given to the students at the end of each unit/topic and will be evaluated at regular interval. Surprise tests/Quizzes/Tutorials will be conducted. The course includes a laboratory, where students have an opportunity opportunity to build an appreciation for the concepts being taught in lectures. Minimum ten experiments shall be there in the laboratory related to course contents.

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Reference Books: List of Reference Books (Organic Chemistry)  Advanced Organic Chemistry by Arun Bahl and B.S.Bahl  Text Book of Organic Chemistry for BSc students by B.S. Bahl  Organic Chemistry by Morrison and Boyd  Fundamentals of Organic Chemistry by Solomon, John Wiley.  Textbook of Organic Chemistry by P.L. Son Soni and H.M. Chawla  March’s Advanced Organic Chemistry Reactions, Mechanism and Structure by Michael B Smith and Jerry March  Reaction Mechanisms and Reagents in Organic Chemistry by Gurudeep R. Chatwal  Advanced Organic Reaction Mechanism by N. Tewari  Organic Chemistry by I.L.Finar List of Reference Books (Spectroscopy)  Spectrometric identification of organic compounds By Silverstrin Bassler (16th Editim)  Elementary organic spectroscopy by Y. R. Sharma.  Spectroscopy of organic compounds by John R. Dyer. Dyer  Spectroscopy of organic compounds by P. S. Kalsi  Chemical Application of Group theory by F Albert Cotton  Symmetry in chemistry by H. M. Jahe.  Molecular spectroscopy by B. K. Sharma.  Organic Spectroscopy by B. K. Sharma

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