Ariff BONGSO PhD (Canada), M.Sc. (Canada), D.Sc. (Singapore), D.Sc.(honoris causa ) (Sri Lanka), D.V.M. (Ceylon), F.S.L.C.O.G. (Sri Lanka), F.R.C.O.G. (ad eundem) (United Kingdom) Research Professor Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore 119074 Phone: 67724129 E-mail:[email protected]
MAJOR RESEARCH INTERESTS 1. Clinical embryology and human in vitro fertilization 2. Human sperm assessment and improvement 3. Cytogenetics of reproductive failure 4. Human embryonic stem cell biology
RECENT REPRESENTATIVE PUBLICATIONS 1. 2. 3.
4. 5. 6. 7. 8. 9. 10. 11. 12.
Reubinoff, BE, MF Pera, CY Fong, AO Trounson and A Bongso, Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nature Biotechnology, 18, 4 (2000): 399-404. Saritha, KR and A Bongso, Comparative evaluation of fresh and washed human sperm cryopreserved in vapour and liquid phases of liquid nitrogen. Journal of Andrology, 22 (2001): 857-862. Fong, CY, A Bongso, H Sathananthan, KC Ho and SC Ng, Ultrastructural observations of enzymatically treated human blastocysts: zona-free blastocyst transfer and rescue of blastocysts with hatching difficulties. Hum Reprod, 16 (2001): 540-546. Bandularatne, E and A Bongso, Evaluation of human sperm function after repeated freezing and thawing. Journal of Andrology, 23, 2 (2002): 242-249. Richards, M, CY Fong, WK Chan, PC Wong and A Bongso, Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nature Biotechnology, 20, 9 (2002): 933-936. Rangappa, S, VG Reddy, EH Lee, A Bongso and EKW Sim, Non-haemopoietic stem cells differentiate into cardiomyocyte-like cells in the internal milieu of the myocardium. J of Heart and Lung Transpl, 21, 1 (2002): 162-163. Ranggapa, S, F Chen, EH Lee, A Bongso and EKW Sim, Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes. Annals of Thoracic Surgery, 75 (2003): 775-779. Richards, M, S Tan, CY Fong, A Biswas, WK Chan and A Bongso, Comparative evaluation of various human feeders for prolonged undifferentiated growth of human embryonic stem cells. Stem Cells (2003): 21: 546-556. Richards M, CY Fong, S Tan, WK Chan, A Bongso, An efficient and safe xeno-free cryopreservation method for the storage of human embryonic stem cells. Stem Cells, 22 (2004): 779-789. Richards, M, SP Tan, JH Tan, WK Chan, A Bongso. The transcriptome profile of human embryonic stem cells as defined by SAGE. Stem Cells, 22, (2004): 51-64. Bongso A and S. Tan, Human blastocyst culture and derivation of embryonic stem cell lines. Stem Cell Reviews, 1: (2005): 1-12. Kueh J, M Richards, SW Ng, WK Chan, A. Bongso, The search for factors in human feeders that support the derivation and propagation of human embryonic stem cells: preliminary studies using transcriptome filing by SAGE. Fertil and Steril 85 (2006): 1843-1846. Richards M, WK Chan, A. Bongso, Reverse SAGE characterization of orphan SAGE tags from human embryonic stem cells identifies the presence of novel transcripts and antisense transcription of key pluripotency genes. Stem Cells, 24: (2006): 1162-1173. Fong CY, M Richards, A. Bongso, Unsuccessful derivation of human embryonic stem cell lines from pairs of human blastomeres. Reprod BioMed Online, 13: (2006): 295-300.